Clusters

 


Explanation of Gene ontology symbols
cluster01 (n = 130)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
extracellular spaceGO:000561531C
integral to membraneGO:001602123C
membraneGO:001602013C
hydrolase activityGO:001678710F
extracellular matrixGO:000557810C
defense responseGO:00069529P
proteolysis and peptidolysisGO:00065088P
immune responseGO:00069557P
nucleusGO:00056347C
antigen processing, exogenous antigen via MHC class IIGO:00198866P
MHC class II receptor activityGO:00450126F
antigen presentation, exogenous antigenGO:00198846P
receptor activityGO:00048725F
cell adhesionGO:00071555P
transportGO:00068104P
DNA bindingGO:00036774F
metallopeptidase activityGO:00082374F
extracellularGO:00055764C
extracellular matrix structural constituentGO:00052014F
metalloendopeptidase activityGO:00042224F
intracellular signaling cascadeGO:00072424P
zinc ion bindingGO:00082704F
calcium ion bindingGO:00055094F
ATP bindingGO:00055244F
structural molecule activityGO:00051984F
peptidase activityGO:00082333F
biological_process unknownGO:00000043P
oxidoreductase activityGO:00164913F
trypsin activityGO:00042953F
regulation of transcription, DNA-dependentGO:00063553P
protein serine/threonine kinase activityGO:00046743F
plasma membraneGO:00058863C
calmodulin bindingGO:00055163F
kinase activityGO:00163013F
transferase activityGO:00167403F
collagenGO:00055813C
extracellular matrix structural constituent conferring tensile strengthGO:00300203F
cytoskeletonGO:00058563C
protein bindingGO:00055153F
chymotrypsin activityGO:00042633F
cytoskeleton organization and biogenesisGO:00070103P

 


Implicit Annotations

NameIDCountAspect

 

 

cluster02 (n = 18)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160215C
extracellular spaceGO:00056154C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster03 (n = 35)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160219C
membraneGO:00160205C
protein bindingGO:00055154F
transportGO:00068103P
hydrolase activityGO:00167873F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster04 (n = 11)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160213C
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster05 (n = 55)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
hydrolase activityGO:001678710F
extracellular spaceGO:000561510C
proteolysis and peptidolysisGO:00065089P
serine-type endopeptidase activityGO:00042527F
trypsin activityGO:00042956F
integral to membraneGO:00160216C
chymotrypsin activityGO:00042636F
peptidase activityGO:00082334F
tissue kallikrein activityGO:00042933F
catalytic activityGO:00038243F
membraneGO:00160203C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster06 (n = 4)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect

 


Implicit Annotations

NameIDCountAspect

 

 

cluster07 (n = 48)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160218C
oxidoreductase activityGO:00164914F
catalytic activityGO:00038244F
metabolismGO:00081524P
extracellular spaceGO:00056154C
transportGO:00068103P
DNA bindingGO:00036773F
fatty acid metabolismGO:00066313P
cytoplasmGO:00057373C
peroxisomeGO:00057773C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster08 (n = 26)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
extracellular spaceGO:00056154C
nucleusGO:00056343C
integral to membraneGO:00160213C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster09 (n = 34)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160216C
inflammatory responseGO:00069543P
metabolismGO:00081523P
immune responseGO:00069553P
transferase activityGO:00167403F
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster10 (n = 38)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
hydrolase activityGO:00167874F
peroxisomeGO:00057774C
integral to membraneGO:00160214C
mitochondrionGO:00057393C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster11 (n = 33)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
nucleusGO:00056343C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster12 (n = 34)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160216C
extracellular spaceGO:00056156C
nucleusGO:00056343C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster13 (n = 29)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
hydrolase activityGO:00167876F
integral to membraneGO:00160216C
oxidoreductase activityGO:00164915F
mitochondrionGO:00057395C
metabolismGO:00081524P
membraneGO:00160203C
ATP bindingGO:00055243F
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster14 (n = 22)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
nucleusGO:00056344C
transportGO:00068103P
molecular_function unknownGO:00055543F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster15 (n = 170)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:001602126C
extracellular spaceGO:000561525C
immune responseGO:000695514P
membraneGO:001602014C
hydrolase activityGO:001678711F
receptor activityGO:000487210F
sugar bindingGO:00055296F
defense responseGO:00069526P
protein bindingGO:00055156F
actin bindingGO:00037795F
intracellular signaling cascadeGO:00072425P
plasma membraneGO:00058865C
proteolysis and peptidolysisGO:00065085P
nucleusGO:00056345C
integral to plasma membraneGO:00058875C
ATP bindingGO:00055245F
transmembrane receptor activityGO:00048884F
peptidase activityGO:00082334F
transportGO:00068104P
extracellularGO:00055764C
heterophilic cell adhesionGO:00071574P
neutrophil chemotaxisGO:00305934P
developmentGO:00072754P
transferase activityGO:00167404F
calcium ion bindingGO:00055094F
cytosolGO:00058293C
biological_process unknownGO:00000043P
proteasome core complex (sensu Eukarya)GO:00058393C
cysteine-type peptidase activityGO:00082343F
GTP bindingGO:00055253F
signal transductionGO:00071653P
apoptosisGO:00069153P
regulation of cell cycleGO:00000743P
antigen processing, exogenous antigen via MHC class IIGO:00198863P
endopeptidase activityGO:00041753F
intracellularGO:00056223C
transporter activityGO:00052153F
cytokine activityGO:00051253F
ubiquitin-dependent protein catabolismGO:00065113P
calmodulin bindingGO:00055163F
MHC class II receptor activityGO:00450123F
protein amino acid phosphorylationGO:00064683P
cell adhesionGO:00071553P
cell surface receptor linked signal transductionGO:00071663P
external side of plasma membraneGO:00098973C
antigen presentation, exogenous antigenGO:00198843P

 


Implicit Annotations

NameIDCountAspect

 

 

cluster16 (n = 21)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
hydrolase activityGO:00167873F
integral to membraneGO:00160213C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster17 (n = 9)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect

 


Implicit Annotations

NameIDCountAspect

 

 

cluster18 (n = 22)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
metabolismGO:00081523P

 


Implicit Annotations

NameIDCountAspect

 

 

cluster19 (n = 86)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:001602114C
hydrolase activityGO:00167877F
transportGO:00068106P
membraneGO:00160206C
mitochondrionGO:00057394C
proteolysis and peptidolysisGO:00065084P
extracellular spaceGO:00056154C
peptidase activityGO:00082333F
ion transportGO:00068113P
oxidoreductase activityGO:00164913F
endoplasmic reticulumGO:00057833C
transporter activityGO:00052153F
transferase activityGO:00167403F
integral to plasma membraneGO:00058873C
ATP bindingGO:00055243F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster20 (n = 29)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
ATP bindingGO:00055245F
mitochondrionGO:00057393C
hydrolase activityGO:00167873F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster21 (n = 29)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
membraneGO:00160207C
integral to membraneGO:00160217C
transportGO:00068104P
integral to plasma membraneGO:00058874C
transporter activityGO:00052153F
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster22 (n = 31)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
regulation of transcription, DNA-dependentGO:00063555P
transportGO:00068103P
DNA bindingGO:00036773F
nucleusGO:00056343C
membraneGO:00160203C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster23 (n = 111)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
extracellular spaceGO:000561517C
integral to membraneGO:001602111C
nucleusGO:00056349C
DNA bindingGO:00036777F
regulation of transcription, DNA-dependentGO:00063557P
protein bindingGO:00055157F
transcription factor activityGO:00037007F
cytokine activityGO:00051256F
calcium ion bindingGO:00055096F
inflammatory responseGO:00069545P
transcription factor complexGO:00056675C
cellular_component unknownGO:00083724C
signal transductionGO:00071654P
immune responseGO:00069554P
chemokine activityGO:00080094F
plasma membraneGO:00058864C
membraneGO:00160204C
receptor activityGO:00048724F
cytoplasmGO:00057374C
chemotaxisGO:00069354P
biological_process unknownGO:00000043P
regulation of cell cycleGO:00000743P
extracellularGO:00055763C
molecular_function unknownGO:00055543F
developmentGO:00072753P
extracellular matrixGO:00055783C
cytoskeletonGO:00058563C
cytoskeleton organization and biogenesisGO:00070103P

 


Implicit Annotations

NameIDCountAspect

 

 

cluster24 (n = 25)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
extracellular spaceGO:00056154C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster25 (n = 15)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster26 (n = 29)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
extracellular spaceGO:00056156C
mitochondrionGO:00057394C
integral to membraneGO:00160214C
kinase activityGO:00163013F
transferase activityGO:00167403F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster27 (n = 33)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
cytoplasmGO:00057374C
integral to membraneGO:00160214C
extracellular spaceGO:00056154C
immune responseGO:00069553P
nucleusGO:00056343C
membraneGO:00160203C
protein bindingGO:00055153F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster28 (n = 77)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:001602110C
nucleusGO:00056349C
protein bindingGO:00055158F
extracellular spaceGO:00056158C
intracellularGO:00056225C
regulation of transcription, DNA-dependentGO:00063555P
DNA bindingGO:00036774F
hydrolase activityGO:00167874F
membraneGO:00160204C
receptor activityGO:00048724F
small GTPase mediated signal transductionGO:00072643P
GTP bindingGO:00055253F
small monomeric GTPase activityGO:00039253F
protein kinase activityGO:00046723F
protein amino acid phosphorylationGO:00064683P
transferase activityGO:00167403F
ATP bindingGO:00055243F
transcription factor activityGO:00037003F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster29 (n = 43)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160217C
integral to plasma membraneGO:00058874C
transportGO:00068103P
cellular_component unknownGO:00083723C
membraneGO:00160203C
transferase activityGO:00167403F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster30 (n = 39)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
transferase activityGO:00167404F
ATP bindingGO:00055244F
hydrolase activityGO:00167873F
nucleusGO:00056343C
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster31 (n = 14)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect

 


Implicit Annotations

NameIDCountAspect

 

 

cluster32 (n = 120)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:001602116C
extracellular spaceGO:000561514C
membraneGO:001602013C
transportGO:000681010P
mitochondrionGO:00057399C
oxidoreductase activityGO:00164918F
hydrolase activityGO:00167876F
carrier activityGO:00053865F
electron transportGO:00061185P
ion transportGO:00068114P
nucleusGO:00056344C
receptor activityGO:00048724F
calcium ion bindingGO:00055094F
mitochondrial inner membraneGO:00057433C
metabolismGO:00081523P
bindingGO:00054883F
proteolysis and peptidolysisGO:00065083P
integral to plasma membraneGO:00058873C
cytoplasmGO:00057373C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster33 (n = 29)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
extracellular spaceGO:00056158C
integral to membraneGO:00160217C
membraneGO:00160203C
receptor activityGO:00048723F
calcium ion bindingGO:00055093F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster34 (n = 23)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
membraneGO:00160204C
extracellular spaceGO:00056154C
integral to membraneGO:00160213C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster35 (n = 20)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160213C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster36 (n = 21)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
hydrolase activityGO:00167873F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster37 (n = 5)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect

 


Implicit Annotations

NameIDCountAspect

 

 

cluster38 (n = 12)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect

 


Implicit Annotations

NameIDCountAspect

 

 

cluster39 (n = 45)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
extracellular spaceGO:00056158C
integral to membraneGO:00160215C
cell adhesionGO:00071554P
membraneGO:00160203C
receptor activityGO:00048723F
collagenGO:00055813C
extracellular matrixGO:00055783C
extracellular matrix structural constituent conferring tensile strengthGO:00300203F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster40 (n = 68)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160219C
protein bindingGO:00055156F
extracellular spaceGO:00056155C
cellular_component unknownGO:00083724C
transferase activityGO:00167404F
biological_process unknownGO:00000043P
regulation of transcription, DNA-dependentGO:00063553P
hydrolase activityGO:00167873F
kinase activityGO:00163013F
cytoplasmGO:00057373C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster41 (n = 48)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160215C
transferase activityGO:00167404F
regulation of transcription, DNA-dependentGO:00063553P

 


Implicit Annotations

NameIDCountAspect

 

 

cluster42 (n = 13)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160215C
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster43 (n = 11)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:00160214C
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster44 (n = 20)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect

 


Implicit Annotations

NameIDCountAspect

 

 

cluster45 (n = 32)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
extracellular spaceGO:00056157C
integral to membraneGO:00160215C
cell adhesionGO:00071553P
protein bindingGO:00055153F

 


Implicit Annotations

NameIDCountAspect

 

 

cluster46 (n = 109)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
integral to membraneGO:001602120C
extracellular spaceGO:000561519C
membraneGO:001602012C
receptor activityGO:000487210F
integral to plasma membraneGO:00058877C
protein bindingGO:00055157F
nucleusGO:00056346C
transferase activityGO:00167406F
defense responseGO:00069525P
inflammatory responseGO:00069544P
protein serine/threonine kinase activityGO:00046744F
protein kinase activityGO:00046724F
rotein-tyrosine kinase activityGO:00047134F
protein amino acid phosphorylationGO:00064684P
ATP bindingGO:00055244F
transportGO:00068103P
ion transportGO:00068113P
signal transductionGO:00071653P
DNA bindingGO:00036773F
intracellularGO:00056223C
immune responseGO:00069553P
ion channel activityGO:00052163F
intracellular signaling cascadeGO:00072423P
hydrolase activityGO:00167873F
cell growth and/or maintenanceGO:00081513P
plasma membraneGO:00058863C
proteolysis and peptidolysisGO:00065083P

 


Implicit Annotations

NameIDCountAspect

 

 

cluster47 (n = 16)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
nucleic acid bindingGO:00036763F
receptor activityGO:00048723F
integral to membraneGO:00160213C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster48 (n = 3)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect

 


Implicit Annotations

NameIDCountAspect

 

 

cluster49 (n = 25)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
nucleusGO:00056343C
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 

cluster50 (n = 20)   Explicit Annotations  Implicit Annotations  Details  

Explicit Annotations

NameIDCountAspect
isomerase activityGO:00168533F
integral to membraneGO:00160213C
extracellular spaceGO:00056153C

 


Implicit Annotations

NameIDCountAspect

 

 


The Gene Ontology Consortium provides a dynamic controlled vocabulary of biological functions. Associations between genes or gene products and GO terms are available from the Gene Ontology website. Functional annotations are divided into three categories:

The terms in GO form a directed acyclic graph (DAG), such that specific terms are children of more general terms. Collaborating databases generate gene association files consisting of links between GO terms and genes or gene products. Generally, these annotations are at the most specific level possible. The Ontologizer shows these annotations as "Explicit Annotations". However, the annotated genes (or gene products) are understood to share the attributes of the parent nodes. The Controller shows these as "Implicit Annotations".

Each GO term represented by a GO_id of the form GO:nnnnnnn, where nnnnnnn is a unique zero-padded integer of seven digits, and a descriptive name. The Gene Ontology documentation offers more details.

The following files were used to generate these pages:

These files were generated by the Ontologizer