cluster15   (n = 170 )

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Gene Ontology Annotations
GeneMolecular functionBiological processCellular component
MGI:1910647
      
MGI:8765
      
MGI:1347080
  • protein binding (GO:0005515)
  • immune response (GO:0006955)
  • nucleus (GO:0005634)
MGI:1334470
      
MGI:30829
      
MGI:1099443
  • transferase activity (GO:0016740)
  • methyltransferase activity (GO:0008168)
  • nicotinamide N-methyltransferase activity (GO:0008112)
    
MGI:1345275
  • transporter activity (GO:0005215)
  • transport (GO:0006810)
  • iron ion transport (GO:0006826)
  • membrane (GO:0016020)
  • integral to membrane (GO:0016021)
MGI:1278327
  • apoptosis regulator activity (GO:0016329)
  • apoptosis (GO:0006915)
  
MGI:95500
  • receptor activity (GO:0004872)
  • IgG receptor activity (GO:0019770)
  • IgG binding (GO:0019864)
  • cell surface receptor linked signal transduction (GO:0007166)
  • phagocytosis, binding (GO:0006910)
  • phagocytosis, engulfment (GO:0006911)
  • immediate hypersensitivity response (GO:0016068)
  • neutrophil chemotaxis (GO:0030593)
  • mast cell activation (GO:0045576)
  • positive regulation of tumor necrosis factor-alpha biosynthesis (GO:0042535)
  • antigen presentation, exogenous antigen via MHC class I (GO:0042590)
  • positive regulation of inflammatory response (GO:0050729)
  • regulation of immune response (GO:0050776)
  • positive regulation of phagocytosis (GO:0050766)
  • antibody-dependent cellular cytotoxicity (GO:0001788)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
MGI:8761
      
MGI:1349412
  • receptor activity (GO:0004872)
  • sugar binding (GO:0005529)
  
  • membrane fraction (GO:0005624)
MGI:11625
      
MGI:1346088
    
  • membrane (GO:0016020)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
MGI:8762
      
MGI:1923551
      
MGI:15061
      
MGI:109515
  • sugar binding (GO:0005529)
  • respiratory gaseous exchange (GO:0007585)
  • heterophilic cell adhesion (GO:0007157)
  • extracellular space (GO:0005615)
MGI:1099953
      
MGI:29165
      
MGI:98484
  • nucleotide binding (GO:0000166)
  • oligopeptide transporter activity (GO:0015198)
  • ATP-binding cassette (ABC) transporter activity (GO:0004009)
  • ATP binding (GO:0005524)
  • transport (GO:0006810)
  • immune response (GO:0006955)
  • oligopeptide transport (GO:0006857)
  • membrane (GO:0016020)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
  • integral to plasma membrane (GO:0005887)
MGI:88339
    
  • extracellular space (GO:0005615)
  • plasma membrane (GO:0005886)
MGI:1099952
      
MGI:1334480
      
MGI:101940
  • GTPase activator activity (GO:0005096)
  • Rho GDP-dissociation inhibitor activity (GO:0005094)
  
  • cytoplasm (GO:0005737)
MGI:97142
  • receptor activity (GO:0004872)
  • sugar binding (GO:0005529)
  • transmembrane receptor activity (GO:0004888)
  • mannose binding (GO:0005537)
  
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
  • cell surface (GO:0009986)
MGI:8810
      
MGI:97876
  • binding (GO:0005488)
  • transporter activity (GO:0005215)
  • lipid binding (GO:0008289)
  • retinoid binding (GO:0005501)
  • retinol binding (GO:0019841)
  • transport (GO:0006810)
  • retinoid metabolism (GO:0001523)
  
MGI:1909810
      
MGI:1924841
  • helicase activity (GO:0004386)
    
MGI:1346526
  • hydrolase activity (GO:0016787)
  • peptidase activity (GO:0008233)
  • endopeptidase activity (GO:0004175)
  • immune response (GO:0006955)
  • ubiquitin-dependent protein catabolism (GO:0006511)
  • cytosol (GO:0005829)
  • proteasome core complex (sensu Eukarya) (GO:0005839)
  • proteasome complex (sensu Eukarya) (GO:0000502)
MGI:1346527
  • hydrolase activity (GO:0016787)
  • peptidase activity (GO:0008233)
  • endopeptidase activity (GO:0004175)
  • immune response (GO:0006955)
  • ubiquitin-dependent protein catabolism (GO:0006511)
  • cytosol (GO:0005829)
  • proteasome core complex (sensu Eukarya) (GO:0005839)
MGI:1320976
      
MGI:1195998
      
MGI:15074
      
MGI:98230
  • protein transporter activity (GO:0008565)
  • GTP binding (GO:0005525)
  • small monomeric GTPase activity (GO:0003925)
  • protein transport (GO:0015031)
  • small GTPase mediated signal transduction (GO:0007264)
  • intracellular protein transport (GO:0006886)
  • endoplasmic reticulum (GO:0005783)
  • Golgi apparatus (GO:0005794)
MGI:1861431
  • sugar binding (GO:0005529)
  • heterophilic cell adhesion (GO:0007157)
  • integral to membrane (GO:0016021)
MGI:103070
  • MHC class II receptor activity (GO:0045012)
  • defense response (GO:0006952)
  • immune response (GO:0006955)
  • antigen presentation, exogenous antigen (GO:0019884)
  • antigen processing, exogenous antigen via MHC class II (GO:0019886)
  • membrane (GO:0016020)
  • integral to membrane (GO:0016021)
  • external side of plasma membrane (GO:0009897)
MGI:1097736
      
MGI:2681809
      
MGI:19951
      
MGI:88328
  • cytokine activity (GO:0005125)
  • tumor necrosis factor receptor binding (GO:0005164)
  • immune response (GO:0006955)
  • membrane (GO:0016020)
  • integral to membrane (GO:0016021)
MGI:98427
  • receptor activity (GO:0004872)
  • DNA binding (GO:0003677)
  • transmembrane receptor activity (GO:0004888)
  • N-methyltransferase activity (GO:0008170)
  • interleukin-1 receptor activity (GO:0004908)
  • DNA methylation (GO:0006306)
  • defense response (GO:0006952)
  • membrane (GO:0016020)
  • extracellular space (GO:0005615)
  • plasma membrane (GO:0005886)
  • integral to membrane (GO:0016021)
MGI:13249
      
MGI:1918398
      
MGI:2180860
  • transferase activity (GO:0016740)
  • RNA binding (GO:0003723)
  • nucleotidyltransferase activity (GO:0016779)
  • immune response (GO:0006955)
  
MGI:1902176
      
MGI:95895
  • MHC class II receptor activity (GO:0045012)
  • defense response (GO:0006952)
  • immune response (GO:0006955)
  • antigen presentation, exogenous antigen (GO:0019884)
  • antigen processing, exogenous antigen via MHC class II (GO:0019886)
  • membrane (GO:0016020)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
MGI:99448
  • GTP binding (GO:0005525)
    
MGI:1892366
      
MGI:9206
      
MGI:96534
  • chaperone activity (GO:0003754)
  • defense response (GO:0006952)
  • immune response (GO:0006955)
  • plasma membrane (GO:0005886)
  • integral to membrane (GO:0016021)
  • integral to plasma membrane (GO:0005887)
MGI:1903310
      
MGI:96902
  • catalytic activity (GO:0003824)
  • hydrolase activity (GO:0016787)
  • lysozyme activity (GO:0003796)
  • hydrolase activity, acting on glycosyl bonds (GO:0016798)
  • carbohydrate metabolism (GO:0005975)
  • cytolysis (GO:0019835)
  • cell wall catabolism (GO:0016998)
  • extracellular (GO:0005576)
  • extracellular space (GO:0005615)
MGI:13528
      
MGI:1334478
      
MGI:106179
  • protein binding (GO:0005515)
  • intracellular signaling cascade (GO:0007242)
  
MGI:16758
      
MGI:1338762
  • protein binding (GO:0005515)
  • regulation of transcription from Pol II promoter (GO:0006357)
  • nucleus (GO:0005634)
MGI:35430
      
MGI:2135954
  • calcium ion binding (GO:0005509)
    
MGI:2137751
      
MGI:1907961
      
MGI:1195966
  • structural molecule activity (GO:0005198)
  • development (GO:0007275)
  • cell adhesion (GO:0007155)
  • cytoskeleton (GO:0005856)
MGI:1100085
      
MGI:1921997
  • molecular_function unknown (GO:0005554)
  • biological_process unknown (GO:0000004)
  • cellular_component unknown (GO:0008372)
MGI:95925
  • MHC class II receptor activity (GO:0045012)
  • defense response (GO:0006952)
  • immune response (GO:0006955)
  • antigen presentation, exogenous antigen (GO:0019884)
  • antigen processing, exogenous antigen via MHC class II (GO:0019886)
  • membrane (GO:0016020)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
MGI:19335
      
MGI:1099951
      
MGI:1334468
      
MGI:1100086
      
MGI:1289383
      
MGI:19336
      
MGI:22571
      
MGI:1931560
  • helicase activity (GO:0004386)
  • hydrolase activity (GO:0016787)
  • ATP dependent helicase activity (GO:0008026)
  • ATP binding (GO:0005524)
    
MGI:9205
      
MGI:95514
  • transferase activity (GO:0016740)
  • protein kinase activity (GO:0004672)
  • rotein-tyrosine kinase activity (GO:0004713)
  • ATP binding (GO:0005524)
  • cell growth and/or maintenance (GO:0008151)
  • intracellular signaling cascade (GO:0007242)
  • regulation of cell cycle (GO:0000074)
  • protein amino acid phosphorylation (GO:0006468)
  • intracellular (GO:0005622)
MGI:1097937
      
MGI:33069
      
MGI:109186
  
  • intracellular signaling cascade (GO:0007242)
  • electron transport (GO:0006118)
  
MGI:1913416
  • calcium ion binding (GO:0005509)
    
MGI:1195256
  • hydrolase activity (GO:0016787)
  • phospholipase activity (GO:0004620)
  • subtilase activity (GO:0004289)
  • lysophospholipase activity (GO:0004622)
  • phospholipase A2 activity (GO:0004623)
  • lipid catabolism (GO:0016042)
  • phospholipid catabolism (GO:0009395)
  • proteolysis and peptidolysis (GO:0006508)
  
MGI:27929
      
MGI:11623
      
MGI:1095878
      
MGI:1334472
      
MGI:15362
      
MGI:107341
  • hydrolase activity (GO:0016787)
  • peptidase activity (GO:0008233)
  • cysteine-type peptidase activity (GO:0008234)
  • cysteine-type endopeptidase activity (GO:0004197)
  • cathepsin S activity (GO:0004218)
  • proteolysis and peptidolysis (GO:0006508)
  • extracellular space (GO:0005615)
  • lysosome (GO:0005764)
MGI:96429
  
  • immune response (GO:0006955)
  • regulation of transcription, DNA-dependent (GO:0006355)
  • nucleus (GO:0005634)
MGI:2664187
      
MGI:105093
  • calmodulin binding (GO:0005516)
  • actin binding (GO:0003779)
  • smooth muscle contraction (GO:0006939)
  
MGI:96086
  • transcription factor activity (GO:0003700)
  • DNA binding (GO:0003677)
  • development (GO:0007275)
  • regulation of transcription, DNA-dependent (GO:0006355)
  • brain development (GO:0007420)
  • nucleus (GO:0005634)
  • transcription factor complex (GO:0005667)
MGI:1346327
    
  • nucleus (GO:0005634)
MGI:20867
      
MGI:95458
  
  • cell growth and/or maintenance (GO:0008151)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
MGI:1321402
  
  • intracellular signaling cascade (GO:0007242)
  
MGI:1278319
  • receptor activity (GO:0004872)
    
MGI:1205307
      
MGI:105383
  • receptor activity (GO:0004872)
  • transmembrane receptor activity (GO:0004888)
  • interleukin receptor activity (GO:0004907)
  • cell surface receptor linked signal transduction (GO:0007166)
  • membrane (GO:0016020)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
  • integral to plasma membrane (GO:0005887)
MGI:17868
      
MGI:107361
  • hydrolase activity (GO:0016787)
  • aspartic-type endopeptidase activity (GO:0004190)
  • cathepsin E activity (GO:0004193)
  • pepsin A activity (GO:0004194)
  • neutrophil collagenase activity (GO:0008130)
  • proteolysis and peptidolysis (GO:0006508)
  • extracellular space (GO:0005615)
MGI:1924183
      
MGI:1334469
      
MGI:13473
      
MGI:96543
  • growth factor activity (GO:0008083)
  • cytokine activity (GO:0005125)
  • interleukin-1 receptor binding (GO:0005149)
  • cell proliferation (GO:0008283)
  • regulation of cell cycle (GO:0000074)
  • inflammatory response (GO:0006954)
  • immune response (GO:0006955)
  • neutrophil chemotaxis (GO:0030593)
  • positive regulation of chemokine biosynthesis (GO:0045080)
  • positive regulation of interleukin-6 biosynthesis (GO:0045410)
  • extracellular (GO:0005576)
MGI:88345
  • sugar binding (GO:0005529)
  • heterophilic cell adhesion (GO:0007157)
  • defense response (GO:0006952)
  • plasma membrane (GO:0005886)
  • integral to membrane (GO:0016021)
MGI:1345961
  • structural molecule activity (GO:0005198)
  • actin binding (GO:0003779)
  
  • viral capsid (GO:0019028)
MGI:1334479
      
MGI:1911432
      
MGI:29370
      
MGI:102687
  
  • apoptosis (GO:0006915)
  
MGI:29369
      
MGI:98263
  • cytokine activity (GO:0005125)
  • chemokine activity (GO:0008009)
  • signal transduction (GO:0007165)
  • chemotaxis (GO:0006935)
  • immune response (GO:0006955)
  • extracellular (GO:0005576)
  • extracellular space (GO:0005615)
MGI:1096380
  • hydrolase activity (GO:0016787)
  • peptidase activity (GO:0008233)
  • endopeptidase activity (GO:0004175)
  • ubiquitin-dependent protein catabolism (GO:0006511)
  • cytosol (GO:0005829)
  • proteasome core complex (sensu Eukarya) (GO:0005839)
MGI:1903641
      
MGI:1316727
  • translation elongation factor activity (GO:0003746)
  • GTPase activity (GO:0003924)
  • GTP binding (GO:0005525)
  • cell proliferation (GO:0008283)
  • regulation of cell cycle (GO:0000074)
  • G1/S transition of mitotic cell cycle (GO:0000082)
  • protein biosynthesis (GO:0006412)
  • translational elongation (GO:0006414)
  
MGI:1861231
  • sugar binding (GO:0005529)
  • heterophilic cell adhesion (GO:0007157)
  • integral to membrane (GO:0016021)
MGI:1889272
  • calcium-independent cell adhesion molecule activity (GO:0016347)
  • protein binding (GO:0005515)
  • cell adhesion (GO:0007155)
  • synaptogenesis (GO:0007416)
  • integral to membrane (GO:0016021)
  • synaptic vesicle (GO:0008021)
  • synapse (GO:0045202)
MGI:1320978
      
MGI:33623
      
MGI:1195289
      
MGI:1278325
      
MGI:8764
      
MGI:1918098
      
MGI:95496
  • receptor activity (GO:0004872)
  • transmembrane receptor activity (GO:0004888)
  • IgE binding (GO:0019863)
  • signal transduction (GO:0007165)
  • cell surface receptor linked signal transduction (GO:0007166)
  • humoral defense mechanism (sensu Vertebrata) (GO:0016064)
  • phagocytosis, engulfment (GO:0006911)
  • neutrophil chemotaxis (GO:0030593)
  • positive regulation of interleukin-10 biosynthesis (GO:0045082)
  • positive regulation of tumor necrosis factor-alpha biosynthesis (GO:0042535)
  • antigen presentation, exogenous antigen via MHC class I (GO:0042590)
  • defense response to pathogenic bacteria (GO:0042830)
  • positive regulation of inflammatory response (GO:0050729)
  • regulation of immune response (GO:0050776)
  • positive regulation of immune response (GO:0050778)
  • positive regulation of phagocytosis (GO:0050766)
  • membrane (GO:0016020)
  • plasma membrane (GO:0005886)
  • integral to plasma membrane (GO:0005887)
  • lipid raft (GO:0045121)
  • external side of plasma membrane (GO:0009897)
MGI:11237
      
MGI:104903
  
  • organogenesis (GO:0009887)
  • negative regulation of growth (GO:0045926)
  • extracellular matrix (GO:0005578)
  • extracellular space (GO:0005615)
  • integral to plasma membrane (GO:0005887)
MGI:1277211
    
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
MGI:1201785
  • ion channel activity (GO:0005216)
  • ion transport (GO:0006811)
  • membrane (GO:0016020)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
MGI:14868
      
MGI:8809
      
MGI:1289514
      
MGI:1289435
      
MGI:1343098
  • calcium ion binding (GO:0005509)
  • biological_process unknown (GO:0000004)
  • cellular_component unknown (GO:0008372)
MGI:1204668
      
MGI:1933397
  • receptor activity (GO:0004872)
  • scavenger receptor activity (GO:0005044)
  
  • membrane (GO:0016020)
  • extracellular space (GO:0005615)
MGI:1913391
  
  • immune response (GO:0006955)
  • integral to membrane (GO:0016021)
MGI:34682
      
MGI:10144
      
MGI:1927135
  • enzyme activator activity (GO:0008047)
  • growth factor activity (GO:0008083)
  • protein kinase inhibitor activity (GO:0004860)
  • actin binding (GO:0003779)
  • protein amino acid phosphorylation (GO:0006468)
  • intracellular (GO:0005622)
MGI:108071
  • signal transducer activity (GO:0004871)
  • receptor binding (GO:0005102)
  • development (GO:0007275)
  • cell-cell signaling (GO:0007267)
  • signal transduction (GO:0007165)
  • Wnt receptor signaling pathway (GO:0016055)
  • frizzled-2 signaling pathway (GO:0007223)
  • organogenesis (GO:0009887)
  • extracellular (GO:0005576)
  • extracellular space (GO:0005615)
MGI:8763
      
MGI:9792
      
MGI:96611
  • receptor activity (GO:0004872)
  • development (GO:0007275)
  • cell adhesion (GO:0007155)
  • cell-matrix adhesion (GO:0007160)
  • integrin-mediated signaling pathway (GO:0007229)
  • neutrophil chemotaxis (GO:0030593)
  • cellular extravasation (GO:0045123)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
  • integrin complex (GO:0008305)
MGI:107752
  • motor activity (GO:0003774)
  • calmodulin binding (GO:0005516)
  • actin binding (GO:0003779)
  • ATP binding (GO:0005524)
  • cytoskeleton organization and biogenesis (GO:0007010)
  • cytoskeleton (GO:0005856)
  • myosin (GO:0016459)
MGI:8807
      
MGI:29945
      
MGI:1333743
      
MGI:1277114
  • receptor activity (GO:0004872)
  
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
MGI:1205223
      
MGI:1889679
  • molecular_function unknown (GO:0005554)
  • transporter activity (GO:0005215)
  • biological_process unknown (GO:0000004)
  • transport (GO:0006810)
  • ion transport (GO:0006811)
  • membrane (GO:0016020)
  • integral to membrane (GO:0016021)
MGI:96907
  • calmodulin binding (GO:0005516)
  • actin binding (GO:0003779)
  
  • membrane (GO:0016020)
MGI:1334481
      
MGI:97810
  • hydrolase activity (GO:0016787)
  • protein binding (GO:0005515)
  • phosphoprotein phosphatase activity (GO:0004721)
  • protein-tyrosine-phosphatase activity (GO:0004725)
  • cellular defense response (GO:0006968)
  • transmembrane receptor protein tyrosine phosphatase signaling pathway (GO:0007185)
  • protein amino acid dephosphorylation (GO:0006470)
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
  • external side of plasma membrane (GO:0009897)
MGI:108046
    
  • integral to membrane (GO:0016021)
  • lysosome (GO:0005764)
MGI:8760
      
MGI:106038
    
  • extracellular space (GO:0005615)
  • integral to membrane (GO:0016021)
MGI:1314504
      
MGI:107823
  • hydrolase activity (GO:0016787)
  • cysteine-type peptidase activity (GO:0008234)
  • cysteine-type endopeptidase activity (GO:0004197)
  • cathepsin K activity (GO:0004216)
  • proteolysis and peptidolysis (GO:0006508)
  • extracellular space (GO:0005615)
MGI:9204
      
MGI:11326
      
MGI:1334482
      
MGI:15071
      
MGI:96544
  • hydrolase activity (GO:0016787)
  • cysteine-type peptidase activity (GO:0008234)
  • caspase activity (GO:0030693)
  • apoptosis (GO:0006915)
  • proteolysis and peptidolysis (GO:0006508)
  • induction of apoptosis (GO:0006917)
  • intracellular (GO:0005622)
MGI:97596
  • transferase activity (GO:0016740)
  • calcium ion binding (GO:0005509)
  • protein binding (GO:0005515)
  • protein kinase activity (GO:0004672)
  • protein serine/threonine kinase activity (GO:0004674)
  • rotein-tyrosine kinase activity (GO:0004713)
  • protein kinase C activity (GO:0004697)
  • calcium channel regulator activity (GO:0005246)
  • ATP binding (GO:0005524)
  • intracellular signaling cascade (GO:0007242)
  • protein amino acid phosphorylation (GO:0006468)
  • calcium ion homeostasis (GO:0006874)
  • calcium ion transport (GO:0006816)
  
MGI:1095877
      
MGI:15072
      
MGI:12366
      
MGI:8759
      
MGI:1195999
      
MGI:8808
      

 

These files were generated by the Ontologizer

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