Yu Rang Park, Ph.D. Post-Doctoral Fellow Seoul National University Biomedical Informatics (SNUBI)/ Systems Biomedical Informatics Research Center College of Medicine, Seoul National University 28 Yongon-dong Chongno-gu, Seoul 110799, Korea Email: kirarang@snu.ac.kr Phone: +82-2-470-8319

Research and Interests :

• Achieving semantic interoperability in biomedical domain
  • BMESH : International standard(ISO/IEC 11179) based metadata registry for biomedical data interpretation
  • Data model creation (TMA-OM, CaGe-OM,TMA-TAB)
• Development of Clinical Trial Management System
  • BioEMR : an integrative framework for clinical trial and research with multiple genomic technologies.
  • PhactaX: Clinical Trial Process Management System Development
• Ontology creation and correction
  • Clinical Document Ontology: A Simple Classification Scheme for Data Elements of Clinical Documents Based on Semantics
  • GOChase : correcting semantic and syntactic inconsistencies from Gene ontology-based annotations for gene product

Education & Experience :

• 2003 ~ present : Researcher in Seoul National University Biomedical Informatics (SNUBI) Lab. at Seoul National University, College of Medicine, Seoul
  
• 2006 ~ 2012 : Ph.D. in Molecular and Genomic Medicine, Seoul National University, College of Medicine, Seoul
  
• 2004 ~ 2006 : M.S. in Molecular and Genomic Medicine, Seoul National University, College of Medicine, Seoul
  
• 1999 ~ 2003 : B.S. in Multimedia Communication Engineering at Seoul Women's University, Seoul

• By project
  • 2012.05 ~ present - Development of method for achieving semantic interoperability of health data exchange using international standard for metadata registry, National Research Foundation of Korea.
    
  • 2010.09 ~ present - Systems Biomedical Informatics Research Center. Ministry of Education, Science and Technology, Republic of Korea.
    
  • 2010.05 ~ 2012.03 - Development of integrated clinical trials data repository and CDISC transformer module, Health & Medical Technology R&D Program, Ministry of Health & Welfare, Republic of Korea.
    
  • 2004.12 ~ 2010.10 - Development of Clinical Information and Trial System Using Standard-based Data Modeling of Integrated Biomedical EMR Information Sources. Ministry of Health & Welfare, Repulic of Korea.
    
  • 2008.04 ~ 2010.03 - Development of a Network based e-Clinical Trial System. Health & Medical Technology R&D Program, Ministry of Health & Welfare, Republic of Korea.
    
  • 2008.04 ~ 2008.11 - Development of Integrated Informatics Technologies for Korean Genomic Cohort Projects. Korea centers for Disease Control and Prevention, Repulic of Korea.
    
  • 2007.0X ~ 2008.0X - Development of Integrated Informatics Technologies for Korean Genomic Cohort Projects. Korea centers for Disease Control and Prevention, Repulic of Korea.
    
  • 2006.05 ~ 2008.03 - Development of Clinical Trial Magement system based on cancer controlled vocabulary and metadata registry. Ministry of Health & Welfare, Repulic of Korea.
    

• By application
  • 2012 ~ present - DialysisNet application - Smartpad application
    
  • 2010 ~ 2012 - Continuity of Care Record Plus (CCR+) - Smartphone application
    
  • 2007 ~ 2008 - Clinical Trial Management System(BioEMR)- Web-based application
    
  • 2005 ~ 2006 - Clinico-Histopathological Metadata Registry (CHMR)- Web-based application
    
  • 2003 ~ 2006 - Microarray data management system (xperanto)- Web-based application
    
  • 2005 ~ 2005 - The Korean Journal of Neuropsychiatric Association (KNPA)- Web-based application
    
  • 2005 ~ 2005 - The Korean Society of Medical Informatics (KOSMI)- Web-based application
    
  • 2003 ~ 2005 - Web application for Korean Multi-center Cancer Cohort (KMCC)- Web-based application
    

• Ju Han Kim, Yu Rang Park. Multicenter clinical trial and research management system based on international standard for metadata representation and management. Patent No. 2010-01-129-002469 (2010.04.29)

• 2012
  • Clinical Document Ontology: A Simple Semantic Classification Scheme for Data Elements for Clinical Documents. Yu Rang Park, Young Soo Song, Ju Han Kim (submitted)
  • Prediction of microbial infection of cultured cells using DNA microarray gene-expression profiles of host responses. Yu Rang Park, Tae Su Chung, Young Joo Lee, Yeong Wook Song, Eun Young Lee, Yeo Won Sohn, Sukgil Song, Woong Yang Park, Ju Han Kim. J Korean Med Sci 2012 October;27(10) (SCI)
  • Establishing semantic interoperability in the course of clinical document exchange using international standard for metadata registry. Yu Rang Park, Hyehyeon Kim, Eun Yang An, Ju Han Kim, Hyung H Kim, Raewoon Park, Dongkyun Park, Eun-Young Jung, Ju Han Kim J Korean Med Assoc August 2012;55(8):729-740 (SCIE)

• 2011
  • CDISC Transformer: a metadata-based transformation tool for clinical trial and research data into CDISC standards. Yu Rang Park, Hye Hyun Kim, Hwa Jeong Seo, Ju Han Kim* (accepted) BTIIS (SCIE)
  • GOChase-II: correcting semantic inconsistencies from Gene Ontology-based annotations for gene products. Yu Rang Park, Jihun Kim, Hye Won Lee, Young Jo Yoon, Ju Han Kim* (accepted) BMC Bioinformatic (SCIE)
  • Standard-based integration of heterogeneous large-scale DNA microarray data for improving reusability. Yong Jung, Yu Rang Park, Jihun Kim, Hwa Jeoung Seo, Sang Jay Bien, Ju Han Kim*

• 2010
  • TMA-TAB: A spreadsheet-based document for exchange of tissue microarray data based on the Tissue Microarray-Object Model. Young Soo Song, Hye Won Lee, Yu Rang Park, Do Kyoon Kim, Jaehyun Sim, Hyunseok Peter Kang, Ju Han Kim* Journal of Biomedical Informatics 2010;43:435-441 (2009 Oct 14. [Epub ahead of print] ) (SCI)
    
  • Achieving interoperability for metadata registries using comparative object modeling. Yu Rang Park and Ju Han Kim. Stud Health Technol Inform 2010;160::1136-1139, MedInfo 2010 IOS Press (ISBN 978-1-58603-774-1), Capetown, South Africa. (PMID:20841861)
    
  • CDISC Transformer: Metadata based CDISC standard compliant exporting and importing tool. Yu Rang Park, HyeHyeon Kim, Ju Han Kim* Proceedings of the 2nd International Conference on Internet and 5th Asia Pacific International Conference on Information Science and Technology, Crimson Resort Mactan, Philiphines

• 2008
  • BioEMR: an integrative framework for cancer research with multiple genomic technologies. Yu Rang Park, Yoonjeong Bae, Ju Han Kim*. 2008 AMIA Translational Bioinformatics Summit, San Francisco, California
    

• 2007
  • Cancer Genomics Object Model: an object model for multiple functional genomics data for cancer research. Yu Rang Park, Hye Won Lee, Sung Bum Cho, Ju Han Kim* Stud Health Technol Inform 2007;129(Pt 2): 1235-9, MEDINFO 2007 Proceedings of the 12th World Congress on Health (Medical) Informatics ? Building Sustainable Health Systems, Edited by Klaus A. Kuhn, James R. Warren, Tze-Yun Leong, IOS Press (ISBN 978-1-58603-774-1), Brisbane, Austria.
    
  • PhactaManager: a clinical trial management system incorporating an XML Layer as a database-independent processing platform. Okgu Kim, Yu Rang Park, Young Shin Kim, Seon Ha Kim, Hwa Jung Kim, Ju Han Kim*, Byung Joo Park* J Kor Soc Med Informatics 2007;13(2):99-113
    

• 2006
  • The Tissue Microarray Object Model: a data model for storage, analysis and exchange of tissue microarray experimental data. Hye Won Lee, Yu Rang Park, Jaehyun Shim, Rae Woong Park, Woo Ho Kim, Ju Han Kim. Arch Pathol Lab Med 2006 Jul;130:1004-1013 (SCI)
    
  • GraPT: Genomic interpreteR About Predictive Toxicology. Jung Hoon Woo, Yu Rang Park, Yong Jung, Jihun Kim, Ju Han Kim. Genomics and Informatics 2006 September;4(3);.
    
  • [Poster] Metadata registry and management system based on ISO 11179 for cancer clinical trials information system. Yu Rang Park, Ju Han Kim. American Medical Informatics Association 2006.
    
  • [Poster] Tissue Microarray Object Model and Xperanto-TMA An object-oriented data model and a web-based data management system for tissue microarray data with clinical and histopathologic information. Hye Won Lee, Yu Rang Park, Jae Hyun Sim, Do Kyoon Kim, Young Ji Na, Ju Han Kim. MGED 2006.
    

• 2005
  • GOChase: Correcting Errors from Gene Ontology-based Annotations for Gene Products. Yu Rang Park, Chan Hee Park, Ju Han Kim. Bioinformatics. 2005 Mar;21(6):829-31. Epub 2004 Oct 28. (SCI)
    
  • Xperanto: a web-based integrated system for DNA microarray data management and analysis. Ji Yeon Park, Yu Rang Park, Chan Hee Park, Ji Hoon Kim, Ju Han Kim. Genomics and Informatics 2005 March;3(1):39-42.
    
  • Cancer Genomics Object Model: An Object Model for Cancer Research Using Microarray. Yu Rang Park, Hye Won Lee, Sung Bum Cho, Ju Han Kim, BioInfo 2005
    
  • Implementation of clinical data storage based on Entity-Attribute-Value and ISO/IEC 11179. Yu Rang Park, Hye Jin Kwon, Se Young Kim, Hye Won Lee, Sung Bum Cho, Ju Han Kim. The Korean Society of Medical Informatics 2005;11(Suppl 1):s5-s8
    
  • A database for the effective and systematic management of Tissue Microarray data. Hye Won Lee, Yu Rang Park, Jaehyun Sim, Sung Bum Cho, Woo Ho Kim, Ju Han Kim. The Korean Society of Medical Informatics 2005;11(Suppl 1):s9-s12
    
  • KPRN Repository System for Storing Pharmacogenomcis Data. Chan Hee Park, Su Yeon Lee, Yu Rang Park, Hye Won Lee, Ju Han Kim. The Korean Society of Medical Informatics 2005;11(Suppl 1):s13-s16
    
  • Analysis of the Tissue Microarray using Bayesian Network Classifier. Sung Bum Cho, Yu Rang Park, Hye Won Lee, Woo Ho Kim, Ju Han Kim. The Korean Society of Medical Informatics 2005;11(Suppl 1):s77-s80
    
  • Developing a Data Model for integrative Analysis of DNA microarray, ArrayCGH and Tissue Microarray for Cancer Genomics Research. Hye Won Lee, Yu Rang Park, Woo Ho Kim, Ju Han Kim. The Korean Society of Medical Informatics 2005;11(Suppl 2):s173-s177
    
  • Developing Knowledgebase for Integrated Systems Toxicology. Jung Hoon Woo, Mingoo Kim , Yu Rang Park, Hye Won Lee, Ju Han Kim. The Korean Society of Medical Informatics 2005;11(Suppl 2):s162-s166
    
  • [Poster] Integrating Microarray Gene Expression Object Model and Clinical Document Architecture for Cancer Genomics Research. Yu Rang Park, Hye Won Lee, Ju Han Kim. American Medical Informatics Association 2005.
    

• 2004
  • An Object model for Tissue Microarray. Hye Won Lee, Yu Rang Park, Tae Su Chung, Hwa Jeong Seo, Ju Han Kim. The Korean Society of Medical Informatics 2004;10(Supp1 2):s37-s40.
  • Development of Microarray Gene Expression Database for MicroArray Gene Expression Markup Language. Ji Yeon Park, M.S., Se Young Kim, M.S., Yu Rang Park, B.S., Hwa Jeoung Seo, Ph.D. Ju Han Kim M.D., Ph.D. The Korean Society of Medical Informatics 2004;10(3).
    
  • A Study of Effective Unified Medical Language System Concept Indexing in Radiology Reports. JungAe Lee, Hwa Jeong Seo, Kee Won Kim, Mingoo Kim, Seung Kwon Hong, Yu Rang Park, Ju Han Kim. The Korean Society of Medical Informatics 2004;10(3).
    
  • Integrating Microarray Gene Expression-Object Model and Clinical Document Architecture using Common Data Element. Yu Rang Park, B.S., Ji Yeon Park, M.S., Se Young Kim, M.S., Hwa Jeoung Seo, Ph.D., Jung Ae Lee, M.S., Ju Han Kim M.D., Ph.D. The Korean Society of Medical Informatics 2004;10(Suppl 1):s41-s45.
    
  • Presentation of Document Constraints for Structured Discharge Note According to Clinical Document Architecture. Hwa Jeoung Seo, Ph.D., Seung Kwon Hong M.D., M.P.H., Jung Ae Lee, M.S., Yu Rang Park, B.S., Ju Han Kim M.D., Ph.D. The Korean Society of Medical Informatics 2004;10(Suppl 1):s55-s59.
    
  • A study of effective UMLS concept indexing in radiology reports. Jung Ae Lee, M.S., Hwa Jeoung Seo, Ph.D, Kee Won Kim, M.D., Min Goo Kim, M.D., Seung Kwon Hong M.D., Yu Rang Park, B.S., Ju Han Kim M.D., Ph.D. The Korean Society of Medical Informatics 2004;10(Suppl 1):s65-s69.
    
  • [Poster]Integration of the MAGE-OM and CDA. Yu Rang Park, Ju Han Kim, Ji Yeon Park, Hwa Jeung Seo. 12th International Conference on Intelligent Systems for Molecular Biology(ISMB 2004)
    

• 2003
  • Database Design for Microarray Data Exchange Model MAGE-OM (Microarray Gene Expression-Object Model). Ji Yeon Park, Yu Rang Park, Seog Park, Ju Han Kim. The Korean Society of Medical Informatics 2003;9(3):227-233.