Disease name

아스퍼거 증후군
 Asperger syndrome

Marker gene

Gene symbol Chromosome location Protein name
NLGN3 Xq13.1 Neuroligin-3
NLGN4X Xp22.33 Neuroligin-4, X-linked

Prevalence

>1 / 1000

Inheritance

다유전자, 다인자성

Age of onset

소아기

ICD 10 code

F84.5

MIM number

300494
300497
608631
608638
608781
609954

Summary

Asperger`s syndrome (AS) is a neuro-biological disorder generally considered as belonging to the spectrum of autism. It has been more recently classified as a pervasive developmental disorder. The estimated prevalence is one children in 250; it is thus not a are disease. The disorder appears to be more common in males. It was first described by Dr Hans Asperger, a pediatrician in Austria in 1944. Patients with AS have intellectual capacity within the normal range with, however, a distinct profile of abilities apparent from early childhood. They can exhibit behavioural problems and marked deficiencies in social and communication skills. There is no specific treatment or cure for AS. Interventions are mainly symptomatic and/or rehabilitational.