Disease name

베제트병  (Behcet’s disease)

Study name

베체트병의 발병에서 inflammasome의 역할

Institute

가천의대 길병원

Director

백한주

Email

baekhj@gilhospital.com

Contact

032-460-8426

References

Choi B, Kim J, Lee ES, Bang D, Sohn S. Synthesized pyridine compound derivatives decreased TNF alpha and adhesion molecules and ameliorated HSV-induced inflammation in a mouse model. Eur J Pharmacol. 2011 Feb 17. [Epub ahead of print]  PMID: 21315710

Choi B, Lee ES, Sohn S. Vitamin D3 ameliorates herpes simplex virus-induced Behcet's disease-like inflammation in a mouse model through down-regulation of Toll-like receptors. Clin Exp Rheumatol. 2010 Dec 3. [Epub ahead of print]  PMID: 21269574

Lee M, Choi B, Kwon HJ, Shim JA, Park KS, Lee ES, Sohn S. The role of Qa-2, the functional homolog of HLA-G, in a Behcet's disease-like mouse model induced by the herpes virus simplex. J Inflamm (Lond). 2010 Jun 24;7:31  PMID: 20573271

Kang S, Lee ES, Choi B, Lim HC, Chun M, Lee S, Sohn S. Effects of irradiation on cytokine production in a mouse model of Behcet's disease. Clin Exp Rheumatol. 2009 Jan-Feb;27(1):54-63  PMID: 19327230

Shim J, Byun HO, Lee YD, Lee ES, Sohn S. Interleukin-6 small interfering RNA improved the herpes simplex virus-induced systemic inflammation in vivo Behcet's disease-like mouse model. Gene Ther. 2009 Mar;16(3):415-25  PMID: 19092856

Bang D, Choi B, Kwon HJ, Lee ES, Lee S, Sohn S. Rebamipide affects the efficiency of colchicine for the herpes simplex virus-induced inflammation in a Behcet's disease mouse model. Eur J Pharmacol. 2008 Nov 19;598(1-3):112-7  PMID: 18823974

Choi B, Hwang Y, Kwon HJ, Lee ES, Park KS, Bang D, Lee S, Sohn S. Tumor necrosis factor alpha small interfering RNA decreases herpes simplex virus-induced inflammation in a mouse model. J Dermatol Sci. 2008 Nov;52(2):87-97  PMID: 18585901

Lee SI, Kwon HJ, Lee ES, Yang BC, Bang D, Lee S, Sohn S. Using pCIN-mIL-4 DNA vector to express mRNA and protein and to improve herpes simplex virus-induced Behcet's disease symptoms in mice. Vaccine. 2007 Oct 10;25(41):7047-55  PMID: 17822810

Seo J, Park JS, Nam JH, Bang D, Sohn S, Lee ES, Park KS. Association of CD94/NKG2A, CD94/NKG2C, and its ligand HLA-E polymorphisms with Behcet's disease. Tissue Antigens. 2007 Oct;70(4):307-13  PMID: 17767552

Park KS, Park JS, Nam JH, Bang D, Sohn S, Lee ES. HLA-E*0101 and HLA-G*010101 reduce the risk of Behcet's disease. Tissue Antigens. 2007 Feb;69(2):139-44  PMID: 17257316

Sohn S, Lutz M, Kwon HJ, Konwalinka G, Lee S, Schirmer M. Therapeutic effects of gemcitabine on cutaneous manifestations in an Adamantiades-Behcet's disease-like mouse model. Exp Dermatol. 2004 Oct;13(10):630-4  PMID: 15447723

Lee ES, Kim YA, Kwon HJ, Bang D, Lee S, Sohn S. Thalidomide upregulates macrophage inflammatory protein-1alpha in a herpes simplex virus-induced Behcet's disease-like animal model. Arch Dermatol Res. 2004 Sep;296(4):175-81  PMID: 15290170

Sohn S, Lee ES, Lee SI, Kim YA, Kwon HJ, Bang D, Lee S. Therapeutic effect of thalidomide through cytokine and chemokine regulation in herpes simplex virus-induced Behcet's disease-like animal model. Adv Exp Med Biol. 2003;528:585-9  PMID: 12918770

Sohn S, Bang D, Lee SI, Kim YA, Lee ES, Ha JY, Kim JH, Choi SY, Lee S. Combined treatment with colchicine and Herba Taraxaci (Tarazacum mongolicum Hand.-Mazz.) attenuates Behcet's disease-like symptoms in mice and influences the expressions of cytokines.   PMID: 12757740

Sohn S, Bang D, Lee ES, Kwon HJ, Lee SI, Lee S. Experimental studies on the antiviral agent famciclovir in Behcet's disease symptoms in ICR mice. Br J Dermatol. 2001 Nov;145(5):799-804.  PMID: 11736905

Sohn S, Lee ES, Lee S. The correlation of MHC haplotype and development of Behcet's disease-like symptoms induced by herpes simplex virus in several inbred mouse strains. J Dermatol Sci. 2001 Jul;26(3):173-81  PMID: 11390202

Sohn S, Lee ES, Kwon HJ, Lee SI, Bang D, Lee S. Expression of Th2 cytokines decreases the development of and improves Behcet's disease-like symptoms induced by herpes simplex virus in mice. J Infect Dis. 2001 Apr 15;183(8):1180-6  PMID: 11262199

Sohn S, Lee ES, Bang D, Lee S. Behcet's disease-like symptoms induced by the Herpes simplex virus in ICR mice. Eur J Dermatol. 1998 Jan-Feb;8(1):21-3  PMID: 9649665

Sohn S. Etiopathology of Behcet's disease: herpes simplex virus infection and animal model. Yonsei Med J. 1997 Dec;38(6):359-64. Review  PMID: 9509904

Lee S, Bang D, Cho YH, Lee ES, Sohn S. Polymerase chain reaction reveals herpes simplex virus DNA in saliva of patients with Behcet's disease. Arch Dermatol Res. 1996 Apr;288(4):179-83  PMID: 8967789