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Disease name
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말단거대증
(Acromegaly)
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Study name
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1. 뇌하수체 종양의 생물 표지자를 이용한 진단 및 치료 지침, 치료제 개발 2. 말단비대증 새로운 약물 치료제 개발 3. 뇌하수체 종양 동물 모델 제작 4. 뇌하수체 종양 세포 라인 확립 5. 뇌하수체 기능부전증 환자의 유전적 원인 규명 |
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Institute
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세브란스병원 |
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Director
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이은직 |
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Email
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ejlee423@yuhs.ac |
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Contact
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02-2228-5003 |
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References
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The cyclic pentapeptide d-Arg3FC131, a CXCR4 antagonist, induces apoptosis of somatotrope tumor and inhibits tumor growth in nude mice. Kim JM, Lee YH, Ku CR, Lee EJ. Endocrinology. 2011 Feb;152(2):536-44. Epub 2010 Dec 8.
PMID:
21147876
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Effect of {beta}4 integrin knockdown by RNA interference in anaplastic thyroid carcinoma. Noh TW, Soung YH, Kim HI, Gil HJ, Kim JM, Lee EJ, Chung J. Anticancer Res. 2010 Nov;30(11):4485-92.
PMID:
21115897
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Clinical management and outcome of 36 invasive prolactinomas treated with dopamine agonist. Yang MS, Hong JW, Lee SK, Lee EJ, Kim SH. J Neurooncol. 2010 Nov 24. [Epub ahead of print]
PMID:
21107645
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Carotid atheromatic plaque is commonly associated with hypopituitary men. Kim JY, Hong JW, Rhee SY, Kim CS, Kim DJ, Lee EJ. Pituitary. 2010 Oct 28. [Epub ahead of print]
PMID:
20981493
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Discrimination of prolactinoma from hyperprolactinemic non-functioning adenoma. Hong JW, Lee MK, Kim SH, Lee EJ. Endocrine. 2010 Feb;37(1):140-7. Epub 2009 Nov 14.
PMID:
20963563
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A case of fugitive acromegaly, initially presented as invasive prolactinoma. Lim JS, Ku CR, Lee MK, Kim TS, Kim SH, Lee EJ. Endocrine. 2010 Aug;38(1):1-5. Epub 2010 Apr 24.
PMID:
20960094
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Role of ultrasonography in outcome prediction in subclinical hypothyroid patients treated with levothyroxine. Shin DY, Kim EK, Lee EJ. Endocr J. 2010;57(1):15-22. Epub 2009 Oct 10.
PMID:
19823000
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Predicting recurrence of nonfunctioning pituitary adenomas. Noh TW, Jeong HJ, Lee MK, Kim TS, Kim SH, Lee EJ. J Clin Endocrinol Metab. 2009 Nov;94(11):4406-13. Epub 2009 Oct 9.
PMID:
19820025
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Foxl2, a forkhead transcription factor, modulates nonclassical activity of the estrogen receptor-alpha. Kim SY, Weiss J, Tong M, Laronda MM, Lee EJ, Jameson JL. Endocrinology. 2009 Nov;150(11):5085-93. Epub 2009 Sep 24.
PMID:
19797124
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Absence of activating mutations of CXCR4 in pituitary tumours. Lee YH, Noh TW, Lee MK, Jameson JL, Lee EJ. Clin Endocrinol (Oxf). 2010 Feb;72(2):209-13. Epub 2009 May 16.
PMID:
19473177
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Tumor tissue identification in the pseudocapsule of pituitary adenoma: should the pseudocapsule be removed for total resection of pituitary adenoma? Lee EJ, Ahn JY, Noh T, Kim SH, Kim TS, Kim SH. Neurosurgery. 2009 Mar;64(3 Suppl):62-9; discussion 69-70.
PMID:
19240574
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Functional expression of CXCR4 in somatotrophs: CXCL12 activates GH gene, GH production and secretion, and cellular proliferation. Lee Y, Kim JM, Lee EJ. J Endocrinol. 2008 Nov;199(2):191-9. Epub 2008 Aug 27.
PMID:
18753332
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Splice variants of the forkhead box protein AFX exhibit dominant negative activity and inhibit AFXalpha-mediated tumor cell apoptosis. Lee EJ, Kim JM, Lee MK, Jameson JL. PLoS One. 2008 Jul 23;3(7):e2743.
PMID:
18648506
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