Table s12. Core-periphery structure analysis of a concept lattice for YHS dataset with 100 clusters annotated by the GO biological process category (p < 0.005).

category Clusters, Significantly overrepresented terms
core cluster, 8, 16, 63, 70, 72
biosynthesis
macromolecule biosynthesis
macromolecule metabolism
metabolism
protein biosynthesis
protein metabolism
regulation of protein biosynthesis
regulation of translation
regulation of translational fidelity
ribosomal small subunit assembly and maintenance
ribosomal subunit assembly
ribosome assembly
ribosome biogenesis and assembly
translation
communicating cluster, 6, 7, 12, 25, 32, 34, 38, 59, 64, 77, 78, 84, 92
35S primary transcript processing
RNA metabolism
RNA methylation
RNA modification
amino acid activation
aromatic compound metabolism
citrate metabolism
cytoplasm organization and biogenesis
glutamate biosynthesis
glutamate metabolism
glutamine family amino acid biosynthesis
glutamine family amino acid metabolism
host pathogen interaction
main pathways of carbohydrate metabolism
negative regulation of translation
nucleoside metabolism
nucleotide metabolism
posttranslational protein folding
processing of 20S pre rRNA
protein folding
pyrimidine nucleotide biosynthesis
pyrimidine nucleotide metabolism
rRNA metabolism
rRNA modification
rRNA processing
regulation of biosynthesis
regulation of metabolism
regulation of physiological process
response to copper ion
response to inorganic substance
response to metal ion
response to stimulus
response to stress
ribosomal large subunit biogenesis
ribosome biogenesis
tRNA aminoacylation
tRNA aminoacylation for protein translation
tRNA methylation
tRNA modification
tRNA processing
transcription from Pol I promoter
translational elongation
translational initiation
trehalose catabolism
tricarboxylic acid cycle
vacuolar protein catabolism
peripheral cluster, 1, 3, 5, 9, 11, 21, 23, 29, 30, 31, 40, 41, 42, 44, 49, 51, 52, 53, 55, 58, 60, 67, 68, 69, 71, 74, 79, 80, 86, 88,
93, 97, 98, 99
ATbiosynthesis
ATmetabolism
ATsynthesis coupled electron transport
ATsynthesis coupled proton transport
DNA dependent DNA replication
DNA metabolism
DNA packaging
DNA repair
DNA replication
DNA replication and chromosome cycle
DNA replication initiation
DNA replication synthesis of RNA primer
Golgi vesicle transport
RNA processing
SRdependent cotranslational membrane targeting
SRdependent cotranslational membrane targeting translocation
age dependent general metabolic decline
aging
alcohol biosynthesis
alcohol catabolism
alcohol metabolism
amine metabolism
amino acid and derivative metabolism
amino acid metabolism
anaerobic respiration
apical bud growth
asparagine catabolism
aspartate family amino acid catabolism
aspartate family amino acid metabolism
base excision repair
carbohydrate biosynthesis
carbohydrate catabolism
carbohydrate metabolism
carbohydrate transport
carboxylic acid biosynthesis
carboxylic acid metabolism
catabolism
cell aging
cell cycle
cell death
cell growth and/or maintenance
cell organization and biogenesis
cell proliferation
cellular morphogenesis
cellular physiological process
cellular process
cellular response to nitrogen starvation
chromatin assembly or disassembly
chromatin modification
chromosome condensation
chronological cell aging
cotranslational membrane targeting
death
development
electron transport
energy coupled proton transport down electrochemical gradient
energy derivation by oxidation of organic compounds
energy pathways
ergosterol biosynthesis
ergosterol metabolism
establishment and/or maintenance of chromatin architecture
fatty acid biosynthesis
folic acid and derivative metabolism
gluconeogenesis
glucose catabolism
glucose metabolism
glutathione biosynthesis
glutathione metabolism
glycogen metabolism
glycolysis
glycoprotein biosynthesis
glycoprotein metabolism
hexose biosynthesis
hexose catabolism
hexose metabolism
hexose transport
hydrogen ion homeostasis
hydrogen transport
intracellular transport
isotropic bud growth
late endosome to vacuole transport
leading strand elongation
lipid biosynthesis
lipid metabolism
macromolecule catabolism
methionine metabolism
mitochondrial electron transport succinate to ubiquinone
mitochondrial electron transport ubiquinol to cytochrome c
mitochondrion distribution
mitochondrion inheritance
modification dependent protein catabolism
monosaccharide biosynthesis
monosaccharide catabolism
monosaccharide metabolism
monosaccharide transport
monovalent inorganic cation transport
morphogenesis
mutagenesis
negative regulation of nucleobase nucleoside nucleotide and nucleic acid metabolism
negative regulation of transcription
negative regulation of transcription DNA dependent
nuclear migration
nuclear organization and biogenesis
nuclear positioning
nucleobase nucleoside nucleotide and nucleic acid metabolism
nucleoside phosphate metabolism
nucleotide excision repair
organic acid biosynthesis
organic acid metabolism
oxidative phosphorylation
phospholipid metabolism
postreplication repair
protein Golgi retention
protein Golgi targeting
protein amino acid acetylation
protein amino acid glycosylation
protein catabolism
proteolysis and peptidolysis
proton transport
purine nucleoside triphosphate biosynthesis
purine nucleoside triphosphate metabolism
purine ribonucleoside triphosphate biosynthesis
purine ribonucleoside triphosphate metabolism
pyruvate metabolism
regulation of exit from mitosis
regulation of pH
response to DNA damage stimulus
response to endogenous stimulus
retrograde transport vesicle recycling within Golgi
ribonucleoside triphosphate biosynthesis
ribonucleoside triphosphate metabolism
ribosomal large subunit assembly and maintenance
secretory pathway
sister chromatid cohesion
sodium ion transport
steroid biosynthesis
steroid metabolism
sterol biosynthesis
sterol metabolism
tRNA metabolism
transcription
transcription DNA dependent
transcription from Pol II promoter
transport
tricarboxylic acid cycle intermediate metabolism
ubiquitin dependent protein catabolism
vacuole inheritance
vacuole organization and biogenesis
vesicle mediated transport
independent cluster, 2, 10, 13, 14, 26, 33, 36, 39, 43, 46, 48, 50, 62, 65, 76, 90, 95, 96
Golgi to plasma membrane transport
M phase of mitotic cell cycle
RNA localization
RNA splicing
RNA splicing via transesterification reactions
RNA splicing via transesterification reactions with bulged adenosine as nucleophile
arginine biosynthesis
calcium mediated signaling
cell adhesion
chromosome segregation
conjugation
conjugation with cellular fusion
cyclin catabolism
cytochrome c oxidase biogenesis
di tri valent inorganic cation homeostasis
donor preference
fatty acid metabolism
fatty acid oxidation
glycogen biosynthesis
iron ion transport
loss of chromatin silencing
mRNA localization intracellular
mRNA processing
mating type switching and recombination
membrane fusion
metal ion homeostasis
microtubule nucleation
mitosis
mitotic anaphase
mitotic anaphase B
mitotic cell cycle
mitotic metaphase/anaphase transition
mitotic sister chromatid segregation
mitotic spindle assembly
nuclear mRNA splicing via spliceosome
nuclear membrane organization and biogenesis
nucleocytoplasmic transport
ornithine metabolism
polyamine transport
polyol transport
positive regulation of gene expression epigenetic
protein complex assembly
protein complex assembly multichaperone pathway
protein deubiquitination
regulation of cell size
regulation of glycogen biosynthesis
regulation of meiosis
regulation of transcription mating type specific
response to external stimulus
response to pheromone
sexual reproduction
sister chromatid segregation
spindle assembly
telomerase dependent telomere maintenance
transition metal ion homeostasis
ubiquitin cycle
vesicle fusion