Supplementary Table 3.
Class III: The genes that showed reverse expression patterns between low and high dose
Functional Classification	Gene_ID	Gene_Symbol	Gene_Name	GB_Accession	Low			High
					06h	24h	72 h	06h	24h	72h
Apoptosis	mCG18862.1	Rbm5	RNA binding motif protein 5	BC054729	NC	3.4	NC	NC	NC	-4.7
Carbohydrate metabolism	mCG121684	Man2a1	mannosidase 2, alpha 1	X61172	NC	1.6	NC	NC	NC	-2.1
	mCG11880.2	Mod1	malic enzyme, supernatant	AK077968	NC	NC	1.7	NC	NC	-3.6
	mCG11168.2	Galnt7	UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7	AK033427	NC	-2.7	NC	NC	NC	2.9
	mCG131371.1	9430041C03Rik	RIKEN cDNA 9430041C03 gene	BC057169	NC	NC	1.7	NC	NC	-2.3
Cell proliferation and differentiation	mCG23672.2	Zfp60	zinc finger protein 60	BC031754	NC	NC	-1.5	NC	1.9	NC
	mCG4499.2	_	_	BC049903	NC	2.9	NC	-2.0	NC	NC
Cell structure and motility	mCG68132.2	S100a1	S100 calcium binding protein A1	BC005590	NC	-1.7	NC	NC	NC	1.7
Coenzyme and prosthetic group metabolism	mCG13238.2	AI415282	expressed sequence AI415282	BC026564	NC	1.5	NC	NC	NC	-2.6
Developmental processes	mCG1973.1	Vldlr	very low density lipoprotein receptor	AK036010	-2.8	NC	NC	NC	NC	4.8
	mCG140739.1	Ephb1	Eph receptor B1	BC057301	NC	2.7	NC	NC	NC	-2.8
	mCG11082.1	Igf2	insulin-like growth factor 2	BC053489	NC	NC	-1.7	NC	NC	1.9
Immunity and defense	mCG1965.2	Crry	complement receptor related protein	M23529	-1.6	NC	NC	NC	1.6	NC
	mCG7015.3	Tlr3	toll-like receptor 3	AF355152	NC	NC	2.1	-2.2	NC	NC
	mCG3998.2	BC020188	cDNA sequence BC020188	BC020188	2.1	NC	1.7	NC	-2.4	NC
	mCG3998.2	BC020188	cDNA sequence BC020188	BC020188	2.1	NC	1.7	NC	-2.4	NC
	mCG1036507.2	_	_	AJ231215	2.0	NC	NC	NC	NC	-5.2
Intracellular protein traffic	mCG12827.1	Rabgef1	RAB guanine nucleotide exchange factor (GEF) 1	BC018229	NC	1.6	NC	-1.6	NC	NC
	mCG13918.1	Kif11	kinesin family member 11	BC060670	NC	-1.6	NC	NC	NC	2.4
Lipid, fatty acid and steroid metabolism	mCG128241.2	AU041483	expressed sequence AU041483	BC010485	NC	-1.8	NC	NC	NC	1.9
	mCG134110.2	Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	BC012954	NC	2.3	NC	NC	NC	-4.7
Muscle contraction	mCG18746.1	Ptgds	prostaglandin D2 synthase (brain)	BC038083	NC	NC	-1.8	NC	NC	1.7
Neuronal activities	mCG1492.3	Srr	serine racemase	AK043738	NC	1.5	NC	NC	NC	-1.5
Nucleoside, nucleotide and nucleic acid metabolism	mCG14061.3	Ilf3	interleukin enhancer binding factor 3	BC060599	NC	2.1	NC	-2.9	NC	NC
	mCG118271	Cnot3	CCR4-NOT transcription complex, subunit 3	BC030332	NC	2.2	NC	NC	NC	-3.1
	mCG20037.2	E2f5	E2F transcription factor 5	BC003220	-1.8	NC	NC	NC	NC	2.2
	mCG18182.2	Satb1	special AT-rich sequence binding protein 1	BC011132	NC	NC	-2.0	NC	NC	4.1
	mCG120039	Ifi16	interferon, gamma-inducible protein 16	BC010546	-1.9	NC	NC	NC	NC	2.5
	mCG12488.1	U2af1-rs2	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1, related sequence 2	AK078070	NC	-2.8	NC	NC	NC	1.6
	mCG140146	Dck	deoxycytidine kinase	BC060062	NC	2.9	NC	-2.3	NC	NC
	mCG67535.2	1700012P16Rik	RIKEN cDNA 1700012P16 gene	AY116023	NC	-1.6	NC	NC	NC	1.5
	mCG11969.2	_	_	BC052048	NC	2.1	NC	NC	NC	-2.6
Oncogenesis	mCG2676.2	Vegfa	vascular endothelial growth factor A	AB086118	NC	3.0	NC	NC	NC	-2.4
	mCG13763.2	Zbp1	Z-DNA binding protein 1	AK008179	NC	NC	-1.7	NC	NC	2.6
Oxidative stress	mCG9645.2	Cat	catalase	BC013447	NC	2.8	NC	NC	NC	-5.3
	mCG14666.2	Mt1	metallothionein 1	AK011040	NC	-3.3	NC	NC	NC	5.5
Protein metabolism and modification	mCG115063.1	Rpl36a	ribosomal protein L36a	BC027515	NC	-1.7	NC	NC	NC	1.7
	mCG13420.2	Rps15	ribosomal protein S15	BC010763	NC	-1.5	NC	NC	NC	1.7
	mCG14435.1	Rps8	ribosomal protein S8	BC051446	NC	-1.6	NC	NC	NC	1.6
	mCG117550.1	Hspd1	heat shock protein 1 (chaperonin)	X53584	NC	1.7	1.8	NC	NC	-1.6
	mCG125918.2	B4galt4	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4	BC013492	NC	-1.6	NC	NC	NC	6.2
	mCG125227	Neu3	neuraminidase 3	AB026842	NC	NC	3.2	-1.9	NC	NC
	mCG21147.2	Stk38	serine/threonine kinase 38	BC009658	NC	2.5	2.1	NC	NC	-3.8
	mCG16678.1	Map3k4	mitogen activated protein kinase kinase kinase 4	BC058719	NC	3.0	NC	NC	NC	-2.6
	mCG4195.2	Pacsin2	protein kinase C and casein kinase substrate in neurons 2	BC023502	NC	1.6	NC	NC	NC	-1.8
	mCG4920.2	Dusp22	dual specificity phosphatase 22	BC057944	NC	NC	-2.0	NC	2.2	NC
	mCG125404	Mipep	mitochondrial intermediate peptidase	AK076613	NC	4.2	NC	NC	NC	-2.7
	mCG114994.1	Adam23;AW046396	a disintegrin and metalloprotease domain 23;expressed sequence AW046396	AK046677	-2.1	NC	NC	NC	NC	2.1
Signal transduction	mCG22233.2	S100a13	S100 calcium binding protein A13	BC005687	NC	-2.4	NC	NC	NC	2.8
	mCG15753.2	Nodal	nodal	AK082823	NC	-1.9	NC	1.5	NC	NC
	mCG114454.1	Fgf10	fibroblast growth factor 10	BC048229	NC	-1.8	NC	2.0	NC	NC
	mCG22347.2	Nfkbia	nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha	BC046754	1.9	NC	NC	NC	NC	-2.3
	mCG140838	_	_	AF464178	NC	NC	-2.1	NC	NC	2.8
Transport	mCG1572.1	Atp6v0e	ATPase, H+ transporting, V0 subunit	BC024733	NC	-1.5	NC	NC	NC	1.5
	mCG20078.2	Atp6v1g1	ATPase, H+ transporting, V1 subunit G isoform 1	BC003429	NC	NC	-1.5	NC	NC	1.8
	mCG17448.3	Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25	AK082756	NC	5.0	NC	NC	NC	-29.8
	mCG21591.2	Slc4a4	solute carrier family 4 (anion exchanger), member 4	AF020195	NC	2.0	NC	NC	NC	-1.6
	mCG6964.2	Slc25a15	solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15	AK052758	NC	2.5	NC	NC	NC	-4.5
Biological process unclassified	mCG4792.2	Ankrd3	ankyrin repeat domain 3	BC057871	NC	2.0	NC	NC	NC	-3.6
	mCG148438	C630023L15	hypothetical protein C630023L15	AK083175	NC	NC	-1.8	NC	1.5	NC
	NM_011335.1	Ccl21a;Ccl21c;Ccl21b	chemokine (C-C motif) ligand 21a (leucine);chemokine (C-C motif) ligand 21c (leucine);chemokine (C-C motif) ligand 21b (serine)	BC038120	3.6	NC	NC	NC	NC	-5.2
	mCG6486.2	Csrp2	cysteine and glycine-rich protein 2	AF037208	NC	-1.8	NC	NC	NC	1.8
	mCG12996.2	Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	AK010706	NC	2.0	NC	NC	NC	-2.6
	mCG123913.2	Kif20a	kinesin family member 20A	Y09632	-2.7	NC	NC	NC	NC	4.9
	mCG128978.1	Krtap8-2	keratin associated protein 8-2	D86422	NC	NC	-1.8	NC	1.6	NC
	mCG13011.2	Lass4	longevity assurance homolog 4 (S. cerevisiae)	AK036108	2.0	NC	NC	NC	-1.5	NC
	mCG11595.2	Mrpl33	mitochondrial ribosomal protein L33	BC059722	NC	-2.2	NC	NC	NC	1.8
	mCG127281.1	Mrpl35	mitochondrial ribosomal protein L35	BC028750	NC	-1.5	NC	NC	NC	1.6
	mCG8803.2	Rbx1	ring-box 1	BC056992	NC	-1.5	NC	NC	NC	1.5
	mCG114239.1	Sh3md2	SH3 multiple domains 2	BC060113	1.5	NC	NC	NC	NC	-2.5
	mCG119969.1	Stard4	StAR-related lipid transfer (START) domain containing 4	AK042691	NC	2.3	NC	NC	NC	-1.5
	mCG19387.1	Sugt1	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	BC009167	NC	2.0	NC	NC	-1.5	NC
	mCG4091.1	Tas1r1	taste receptor, type 1, member 1	AF301162	1.8	NC	NC	NC	NC	-3.5
	mCG1355.1	Tmc7	transmembrane channel-like gene family 7	AY263161	2.0	NC	NC	NC	NC	-3.6
	mCG117705.1	Uxt	ubiquitously expressed transcript	AK086822	NC	-1.7	NC	NC	NC	1.6
	mCG9520.2	B130017I01Rik	RIKEN cDNA B130017I01 gene	BC040387	NC	3.0	NC	NC	NC	-3.3
	mCG3696.2	B230339H12Rik	RIKEN cDNA B230339H12 gene	AK088866	NC	2.8	NC	NC	NC	-4.4
	mCG7917.2	BC030417	cDNA sequence BC030417	BC049264	NC	2.5	NC	NC	NC	-5.3
	mCG127144.2	1110001N06Rik	RIKEN cDNA 1110001N06 gene	AK045125	-1.5	NC	NC	-1.4	NC	1.8
	mCG18653.2	2610208M17Rik	RIKEN cDNA 2610208M17 gene	BC066829	NC	NC	1.9	NC	NC	-2.1
	mCG130901.1	2810403B08Rik	RIKEN cDNA 2810403B08 gene	AK080249	-2.7	NC	NC	NC	NC	2.7
	mCG1862.3	4921511I16Rik	RIKEN cDNA 4921511I16 gene	AK089057	NC	-1.8	NC	NC	NC	2.0
	mCG120190.1	6330407G11Rik	RIKEN cDNA 6330407G11 gene	BC003291	NC	2.3	NC	NC	NC	-5.6
	mCG123898	6530404N21Rik	RIKEN cDNA 6530404N21 gene	BC052355	NC	2.3	1.7	-2.8	NC	NC
	mCG9880.2	0610033I05Rik	RIKEN cDNA 0610033I05 gene	AK002739	NC	NC	-2.0	NC	-2.0	NC
	mCG9270.2	1110001J03Rik	RIKEN cDNA 1110001J03 gene	AK009186	NC	-1.7	NC	NC	NC	1.5
	mCG121314.1	1110001O19Rik	RIKEN cDNA 1110001O19 gene	BC052720	NC	-1.7	NC	NC	NC	1.6
	mCG20298.3	1110003H09Rik	RIKEN cDNA 1110003H09 gene	AK088418	NC	-1.6	NC	NC	NC	1.7
	NM_053203.1	1700020M10Rik	RIKEN cDNA 1700020M10 gene	AK006176	NC	-1.7	NC	NC	NC	2.9
	mCG4128.2	1810021J13Rik	RIKEN cDNA 1810021J13 gene	BC034160	NC	-1.7	NC	NC	NC	2.0
	mCG1027455	2610204G22Rik	RIKEN cDNA 2610204G22 gene	AK078249	NC	-2.0	NC	1.5	NC	NC
	mCG17121.3	4833415N24Rik	RIKEN cDNA 4833415N24 gene	AK031214	NC	3.8	NC	-4.0	NC	NC
	mCG6055.1	4933403F05Rik	RIKEN cDNA 4933403F05 gene	BC038695	NC	NC	2.0	NC	NC	-2.5
	mCG5792.2	4933424N09Rik	RIKEN cDNA 4933424N09 gene	BC052150	NC	NC	-2.2	NC	3.0	NC
	mCG17265.2	_	_	BC057025	-1.5	NC	NC	NC	NC	2.8
	mCG16085.2	_	_	AK013636	NC	-1.6	NC	NC	NC	2.9
	mCG6150.2	_	_	AK004417	NC	-2.0	NC	NC	NC	1.6
	mCG113790.1	_	_	AK047836	NC	5.1	NC	NC	NC	-5.1
	AK052349.1	_	_	AK052349	NC	-1.7	-1.6	NC	NC	2.6
	mCG17917.2	_	_	BC034735	NC	2.1	NC	NC	NC	-1.6
	mCG140804	_	_	AK005621	NC	-2.1	NC	NC	NC	2.4
	AK015178.1	_	_	AK015178	-2.3	NC	NC	NC	NC	4.8
	AK082263.1	_	_	AK082263	NC	-1.7	NC	NC	NC	2.2
	AK017999.1	_	_	AK079652	NC	NC	2.4	NC	-1.5	NC
	mCG49479.2	_	_	AK081077	NC	NC	1.6	NC	NC	-3.7
	AK032706.1	_	_	AK032706	2.6	NC	NC	NC	-3.3	NC
	AK084660.1	_	_	AK084660	NC	NC	-1.6	2.2	NC	NC
	mCG147560	_	_	AK028038	-1.8	NC	NC	NC	NC	3.8
	AK035362.1	_	_	AK035362	NC	NC	-3.1	1.8	NC	NC
	AK040552.1	_	_	AK040552	2.2	NC	NC	NC	NC	-4.7
	mCG146318	_	_	AK037207	NC	NC	-1.8	NC	2.0	NC
	AK036087.1	_	_	AK036087	NC	-1.7	NC	NC	NC	1.7
	mCG147162	_	_	AK081400	NC	NC	-2.1	NC	NC	3.5
	AK079455.1	_	_	AK079455	NC	2.5	NC	NC	NC	-4.1
	mCG1034862	_	_	AK009244	NC	-1.8	NC	NC	NC	1.9
	mCG5020.2	_	_	AK015124	NC	NC	-1.7	NC	2.3	NC
	AK045351.1	_	_	AK045351	NC	NC	1.5	NC	NC	-1.7
	AK028971.1	_	_	AK028971	NC	NC	-1.9	1.8	NC	NC
	AK077806.1	_	_	AK077806	NC	3.2	NC	NC	NC	-3.7
	mCG146300	_	_	BC051549	-2.0	NC	NC	NC	NC	2.6
	AK009585.1	_	_	AK009585	NC	-1.8	NC	NC	NC	2.0
	AK037301.1	_	_	AK037301	2.5	NC	NC	NC	NC	-3.5
	mCG144769	_	_	BC056177	NC	-2.2	NC	NC	NC	2.3
	mCG146052	_	_	AK052392	NC	_	2.4	NC	-2.0	NC
	mCG1041502.1	_	_	AK040387	NC	2.8	NC	NC	NC	-2.2
	mCG21143.2	_	_	BC022730	NC	-2.4	NC	NC	NC	2.1
	mCG14143.2	_	_	AK050152	NC	2.0	NC	NC	NC	-1.7
	mCG1252.1	_	_	AK010233	NC	NC	-1.5	NC	NC	1.7
	mCG53839.2	_	_	AK016974	-1.7	NC	NC	NC	NC	1.6
	AK038989.1	_	_	AK038989	NC	NC	2.7	-2.7	NC	NC
*; fold change to control mean value
NC; no change